Mark J Kurth Selected Research

cystic fibrosis transmembrane conductance regulator delta F508

1/2010	Design and synthesis of a hybrid potentiator-corrector agonist of the cystic fibrosis mutant protein DeltaF508-CFTR.
10/2008	Potent s-cis-locked bithiazole correctors of DeltaF508 cystic fibrosis transmembrane conductance regulator cellular processing for cystic fibrosis therapy.

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Mark J Kurth Research Topics

Disease

13	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 01/2017 - 05/2003
12	Cystic Fibrosis (Mucoviscidosis) 01/2019 - 07/2003
3	Neoplasms (Cancer) 10/2021 - 01/2009
3	Cholangitis 11/2011 - 08/2007
2	Constipation 01/2017 - 01/2017
2	Inflammation (Inflammations) 01/2015 - 01/2013
2	Polycystic Kidney Diseases (Polycystic Kidney Disease) 05/2013 - 08/2011
2	Rheumatoid Arthritis 01/2013 - 12/2003
2	Fibrosis (Cirrhosis) 10/2011 - 02/2006
2	B-Cell Lymphoma (Lymphoma, B Cell) 07/2010 - 01/2009
1	Colonic Neoplasms (Colon Cancer) 02/2019
1	Asthma (Bronchial Asthma) 01/2019
1	Infections 01/2019
1	Rhinosinusitis 01/2019
1	Opioid-Induced Constipation 01/2017
1	Hepatitis 11/2014
1	Chemical and Drug Induced Liver Injury 11/2014
1	Neuroblastoma 09/2012
1	Cysts 08/2011
1	Myocardial Infarction 02/2008
1	Neurodegenerative Diseases (Neurodegenerative Disease) 02/2008
1	Stroke (Strokes) 02/2008
1	Lymphoma (Lymphomas) 11/2007
1	Autoimmune Diseases (Autoimmune Disease) 08/2007
1	Sclerosing Cholangitis 12/2003

Drug/Important Bio-Agent (IBA)

10	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 01/2017 - 05/2005
8	Chloride Channels (Chloride Channel)IBA 01/2017 - 05/2005
7	XenobioticsIBA 04/2013 - 11/2003
5	AntibodiesIBA 01/2017 - 05/2005
5	AutoantibodiesIBA 09/2013 - 12/2003
5	AutoantigensIBA 11/2011 - 05/2003
4	Pyruvate Dehydrogenase Complex (Dehydrogenase Complex, Pyruvate)IBA 10/2012 - 05/2003
3	IntegrinsIBA 01/2015 - 11/2007
3	Pyruvic Acid (Pyruvate)IBA 09/2013 - 12/2003
3	Oxidoreductases (Dehydrogenase)IBA 09/2013 - 12/2003
3	2-octynoic acidIBA 11/2011 - 05/2005
2	Secretory Phospholipases A2IBA 01/2015 - 01/2013
2	Proteins (Proteins, Gene)FDA Link 01/2015 - 10/2008
2	Phenylalanine (L-Phenylalanine)FDA Link 12/2014 - 05/2010
2	Integrin alpha4beta1 (VLA-4)IBA 07/2010 - 01/2009
2	Mutant Proteins (Protein, Mutant)IBA 04/2010 - 01/2010
2	cystic fibrosis transmembrane conductance regulator delta F508IBA 01/2010 - 10/2008
2	Cell Surface ReceptorsIBA 01/2009 - 11/2007
2	PeptidomimeticsIBA 01/2009 - 11/2007
2	Urea (Carbamide)FDA LinkGeneric 01/2009 - 11/2007
1	RNA (Ribonucleic Acid)IBA 10/2021
1	Heterocyclic Compounds (Compounds, Heterocyclic)IBA 02/2019
1	Therapeutic UsesIBA 02/2019
1	benzonitrileIBA 02/2019
1	AntiportersIBA 01/2019
1	ChloridesIBA 01/2019
1	AnionsIBA 01/2019
1	Lubiprostone FDA Link 01/2017
1	Scopolamine (Hyoscine)FDA Link 01/2017
1	linaclotideIBA 01/2017
1	Immunoglobulin M (IgM)IBA 01/2017
1	Halothane (Fluothane)FDA Link 11/2014
1	Peptides (Polypeptides)IBA 09/2013
1	Alanine (L-Alanine)FDA Link 09/2013
1	Acetaminophen (Paracetamol)FDA LinkGeneric 10/2012
1	ThiazolesIBA 09/2012
1	Bovine Serum AlbuminIBA 11/2011
1	Pharmaceutical PreparationsIBA 10/2011
1	benzimidazoleIBA 07/2010
1	PyrimidinesIBA 04/2010
1	benzothiazoleIBA 01/2009
1	Oxidants (Oxidizing Agents)IBA 12/2008
1	PyocyanineIBA 12/2008
1	EpitopesIBA 08/2008
1	Interferon-gamma (Interferon, gamma)IBA 08/2008
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2008
1	3- (2,4- dichloro- 5- methoxyphenyl)- 2- sulfanyl- 4(3H)- quinazolinoneIBA 02/2008
1	AcidsIBA 08/2006
1	4-Quinolones (4 Quinolones)IBA 02/2006
1	SulfonamidesIBA 05/2005
1	Food Additives (Food Additive)IBA 05/2005
1	Thioctic Acid (Lipoic Acid)IBA 12/2003

Therapy/Procedure

7	Therapeutics 01/2018 - 07/2003
1	Drug Therapy (Chemotherapy) 02/2019